Prevotella: A Key Player in Ruminal Metabolism

Ruminants are foregut fermenters that have the remarkable ability of converting plant polymers that are indigestible to humans into assimilable comestibles like meat and milk, which are cornerstones of human nutrition.Ruminants establish a symbiotic relationship with their microbiome, and the latter is the workhorse of carbohydrate fermentation.On

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CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest

Abstract Background Cell cycle dysregulation is common in human malignancies, and CDK4/6 inhibitors targeting cell cycle have potential antitumor activity.SHR6390 is a novel small molecule inhibitor specifically targeting the CDK4/6 pathway.However, the role of SHR6390 in esophageal squamous cell carcinoma Glove (ESCC) remains unknown, which will b

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Development, Testing and Results of a Patient Medication Experience Documentation Tool for Use in Comprehensive Medication Management Services

The medication experience is an individual’s subjective experience of taking a medication in daily life and can be at the root of drug therapy problems.It is recommended that the patient-centered approach to comprehensive medication management Braziers (CMM) starts with an understanding of the patient’s medication experience.This study

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